There were distressing scenes in the aftermath as a number of bodies and bikes lay scattered on the road along a trail of destruction.
A nurse, wearing a white mask over her face, ran out of the hospital to help the injured, and was seen pumping a motionless person's chest while trying to revive them.
Eyewitnesses rushed to the scene and heroically tried to push the van off of victims after it had crashed into a pole and finally come to a stop.
The horror crash happened in the Chinese city of Nanning, the capital of its southern Guangxi region near the Vietnam border.
At least one person was killed, but a number of others were severely injured and there were fears the death toll would rise, according to local reports.
The van was "out of control" when it ploughed into pedestrians and motorbike riders on a road in front of the Taoyuan Road District Hospital just after 11.30am on Thursday, said eyewitnesses.
The driver of the van is being questioned by police.
The cause of the crash was not known.
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