Michelle Pearson lost Demi, 15, Brandon, 8, Lacie, 7, and Lia, 3, in the devastating fire in Salford in December 2017.
The 37-year-old mum has been battling to recover after being left in a coma with severe burns to 75 per cent of her body.
Earlier this year, she was filmed in a wheelchair with a tracheostomy tube in her neck and casts on her leg as she released balloons outside hospital.
But last night her mum, Sandra Lever, took to Facebook to tell friends and family her condition had worsened.
She wrote: "We have been reluctant to share Michelle's journey over the past few months as we have been focusing on getting her better.
"Also trying to keep away from the public eye to allow Michelle and the family to grieve.
"However, what people didn't know is that in fact this has been the most challenging time for Michelle and the family.
"Michelle's health has deteriorated in the past 10 weeks, Michelle is still in critical health and still remains in hospital until further notice."
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