The Haitian-American model, whose full name was Cacsmy Brutus, died on Monday after falling ill on a trip to London, her family wrote in an Instagram post.
Cax had lost her leg to lung and bone cancer as a teenager, and was a powerful advocate for women of colour and disabled women in fashion.
"To say that Cax was a fighter would be an understatement," her family's statement said.
"As a cancer survivor, she had grown accustomed to taking on life's several challenges head on and successfully. It is with that same grit... that she fought her last days on earth."
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