The Commissioner for Health, Dr Innocent Vakkai, disclosed this to reporters on Monday in Jalingo, the state capital.
He explained that the ministry has recorded 15 suspected cases of Lassa fever, with only five found to be positive.
Vakkai said the four people said to have died were among the five patients tested positive.
He added that most of the cases came from six local government areas of Bali, Gashaka, Gassol, Ardo-Kola, Jalingo and Ibi.
According to the commissioner, the state government has activated its surveillance system for more case detection and proper treatment.
He noted that efforts were ongoing to create awareness for residents of the state to enlighten them about the symptoms of the disease.
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